PPD CorEvitas Neurology Registries

PPD™ CorEvitas™ Clinical Registries track information about the health status of patients and the care they receive, bringing together large regulatory-grade proprietary data sets to analyze patterns in treatment and outcomes, informing best practices and treatment decisions.

Developed and maintained under the guidance of scientific advisors who are preeminent experts in their fields, these registries feature exceptional data completeness and scientific rigor.

Now enrolling qualified sites for our neurology registries!

CorEvitas Multiple Sclerosis (MS) Registry

Leverage information from this prospective, multi-site, observational study to obtain real-world data and evidence on the comparative effectiveness and safety of approved therapies in patients with MS in the U.S. In addition to analyzing the epidemiology and natural history of the disease, its comorbidities, and current treatment practices, this registry’s data provide a wide range of key outcome measures and opportunities for research.

nurse assisting her elderly patient

Our extensive MS Registry comprises

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Study visits

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Patients

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Neurologists

Examples of the robust outcome measures collected in the CorEvitas MS Registry

  • Relapse rate (12 and 24 months)
  • Timed 25-foot walk (T25-FW)
  • 9-Hole peg test (9-HPT)
  • Symbol digit modalities test (SDMT)
  • Clinical global impression scale (CGI)
  • MS Disability Score: Patient Determined Disease Steps (PDDS)
  • Depression Outcome: Patient Health Questionnaire-2 (PHQ-2)
  • Multiple Sclerosis Impact Scale (MSIS-29)
  • Work Productivity and Activity Impairment (WPAI)
  • Morning Stiffness Visual Analogue Scale
  • Fatigue (shortened, modified Fatigue Impact Scale)
  • Patient Global Impression of Change (PGIC)
  • Pain Numerical Rating Scale

Make these data work for you.

Join our Registry Investigator Network to improve patient health outcomes

PPD CorEvitas Myasthenia Gravis (MG) Registry

Established in 2025

This prospective registry gathers detailed clinician- and patient-reported outcomes data in real-world clinical care settings on the quality of life, daily activities, and muscle activity for individuals with MG. Real-world evidence from this registry aims to inform clinical decision-making for both patients and providers and supports research evaluating existing and emerging therapies for the treatment of MG.

Man with Myasthenia Gravis disease petting dog

Examples of the robust outcome measures collected in the PPD CorEvitas MG Registry

  • Myasthenia Gravis Composite (MGC) Score
  • Manual Muscle Test (MMT)
  • Myasthenia Gravis Impairment Index (MGII)
  • Myasthenia Gravis Foundation of America – Post Intervention Status (MGFA-PIS)
  • Myasthenia Gravis – Activities of Daily Living (MG-ADL)
  • Myasthenia Gravis Quality of Life-15 revised (MGQoL-15r)
  • Quality of Life in Neurological Disorders (Neuro-QoL) – Fatigue, short form
  • EuroQol-5D questionnaire (EQ-5D-5L), EuroQol-visual analogue scales (EQ VAS)
  • Patient reported pain numeric rating scale (NRS)
  • Work productivity and impairment index (WPAI)

Are you interested in utilizing these data?

Join our Registry Investigator Network to improve patient health outcomes

CorEvitas SPHERES Neuromyelitis Optica Spectrum Disorder (NMOSD) Registry

Developed in partnership with the Guthy Jackson Charitable Foundation, the CorEvitas NMOSD Registry provides robust real-world data to improve understanding of NMOSD disease and treatment. These insights help inform research decisions that will improve patients’ lives.

Female patient having an eye exam by an Ophthalmologist

Our NMOSD Registry comprises

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Study visits

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Patients

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Neurologists

Examples of the robust outcome measures collected in the CorEvitas NMOSD Registry

  • Primary Diagnosis
  • Year of onset and diagnosis​ of NMOSD
  • Details of neurological episodes (initial and subsequent relapses)
  • 2015 IPND international consensus diagnostic criteria characteristics
  • Serology Status (AQP4, MOG)
  • EDSS (expanded disability status scale) Step Score
  • Montreal Cognitive Assessment (MoCA)
  • History of Infections
  • Comorbidity and Medical History
  • Modified Fatigue Impact Scale (MFIS)
  • PainDETECT Questionnaire (PD-Q)
  • EuroQol Visual Analogue Scale (EQ-VAS)
  • 5-level EQ-5D version (EQ-5D-5L)
  • Short-Form McGill Pain Questionnaire-2 (SF-MPQ-2)
  • Pain Severity Numeric Rating Scale
  • Patient Health Questionnaire-2 (PHQ-2)
  • Visual Function Questionnaire – Utility Index (VFQ-UI)

Make these data work for you.

Join our Registry Investigator Network to improve patient health outcomes

Contact our team