PPD Evidera Implementation Science
Optimize product uptake and adoption in real-world settings
In the real world, the market approval of a new therapy is no guarantee of its commercial or clinical success. A host of obstacles, including regulatory considerations, patient adherence and persistence, and inflexible clinical workflows can impede the uptake of a new product or health care innovation.
Implementation science uses a combination of proven research experience, scientific expertise and cutting-edge methodologies to anticipate and proactively address barriers before they affect your product’s uptake.
Leverage implementation science research at any stage
There are many reasons for slower-than-expected product uptake, adoption and long-term use. Whether you’re looking to better understand patient retention issues or the impact that adverse events have on product adoption or adherence, implementation science research can provide vital insights that impact a product’s usage at any stage in its life cycle.
Ways you can leverage implementation science:
- Increase patient uptake in clinical trials
- Impact patient retention in clinical trials
- Reduce patient burden with data collection
- Adhere to trial protocols (patient, provider, researcher)
- Generate and test value messages
- Inform product launch strategy
- Assess barriers and facilitate product adoption and uptake
- Understand appropriate infrastructure to support product updates
- Assess patient, provider and system-driven evidence of real-world barriers
- Improve understanding of the product’s risk profile through safety monitoring
- Scale the use of the product for clinical practice from one setting to another
- Sustain use over time
Fill the gap between clinical research and real-world practice
Using scientifically informed theories, strategies and outcomes, our implementation scientists use innovative research approaches to craft a custom plan to close the gap between clinical research and real-world utility. Once the root cause of barriers to uptake, roll-out, scale-up and sustainability have been identified, an effective and efficient strategic path forward is created with the goal of achieving real-world product optimization and utility.
Our robust implementation science solutions have the proven power to help improve your product’s uptake, including:
- Developing strategies to accelerate the adoption, scalability and sustainability of a new product, device or health care innovation
- Conducting contextual analysis of the health care delivery landscape to understand current processes and adoption and integration of new products
- Performing evidence synthesis and developing logic models to guide design and implementation planning
- Using quantitative and qualitative data to evaluate the effectiveness of implementation strategies
- Applying mixed-method approaches to evaluate whether drug safety risk minimization programs are effective in real-world contexts
- Providing bespoke implementation science training to your team to meet specific organizational or therapeutic area needs
Benefit from global expertise and study experience
We have a proven track record of using implementation science to improve the reach, scale-up and sustainability of new products and innovation.
With 25 experts dedicated to implementation science, we are leading the industry through novel and forward-thinking research approaches that transform science and lives.
By combining expertise and operational excellence, we have successfully delivered high-quality implementation science projects for many of the world’s top pharmaceutical companies.
Join the Consortium on Implementation Science Models, Methods & Measures in Drug Development
This consortium is an exciting opportunity to network and collaborate with leading scientists, learn about the latest implementation science research findings, engage in research agenda-setting and more. Membership is free and offers you the opportunity to participate in informative, science-based implementation science webinars, forums and quarterly meetings with other practitioners in industry and academia.
Leading the way in product delivery
Accelerating new or existing products’ adoption, scalability and sustainability is our driving force. When you partner with our team, you have the support and experience of the largest implementation science group in the industry. We’re committed to helping optimize your product’s success and patients’ outcomes through our suite of evidence-based practices.
With our extensive experience conducting a wide range of implementation science studies, we are equipped to deliver projects on time and at the highest quality. From early development to post-marketing, we have the right approach and experience to meet your unique needs.
Outcomes validate success
Empirically supported results are the goal in implementation science. Our three-step approach to product implementation includes:
Understand barriers and facilitators to implementing your product in practice to identify strategies to improve implementation.
Enhance the adoption, implementation and sustainability of your product in practice, while improving patient, provider and system-level outcomes.
Evaluate outcomes to determine if the implementation strategies were effective, what needs refinement and where additional strategies are warranted.
Assess the impact of your implementation plan and provide you with product insights to help achieve its full effectiveness in real-world use.
Case studies
Explore real-world insights gained through implementation science research.
BRIDGE (Phase I) study aims and approach
- A study to identify and address key points in the treatment pathway of patients with Chronic Spontaneous Urticaria (CSU) related to patient diagnosis, referral and treatment escalation. This included the use of patient-reported outcomes (PROs) in clinical practice.
- Phase I methods included a targeted review of documents related to the patient journey, the health care context and analysis of interviews and focus group data (from general practitioners and specialists).
Value and impact
- Analysis provided critical insights into the contextual landscape of the patient journey and clinical care processes for patients with CSU in Italy.
- BRIDGE (Phase I) provided five key recommendations for consideration when reviewing and refining the components of the Urticaria Care Package.
- Results also informed development of the surveys used in Phase II of the study.
AMAZE study aims and approach
- A study to generate evidence on the feasibility, usability, perceived value and potential benefits of the AMAZE™ asthma disease management platform implemented in clinical practice.
- Data collection included patient/clinical site staff surveys, patient longitudinal and cross-sectional qualitative interviews, and patient/clinician app usage metrics data.
Value and impact
- Most participants were satisfied with the AMAZE app, and engagement showed a trend towards engagement being higher for those with poorly controlled asthma; however, overall usage decreased over time.
- Highlighted need for improvements to the app and future studies evaluating optimal level of engagement, timing of completion of features and engaging well-controlled asthmatic patients.
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