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Leveraging decentralized clinical trial strategies to reduce health care disparities

Leveraging decentralized clinical trial strategies to reduce health care disparities

Title page of the white paper, "Leveraging decentralized clinical trial strategies to reduce health care disparities"

Discover how decentralized clinical trial strategies expand access and support trial diversity

Representative clinical trial participation is important for understanding how investigational therapies perform across the populations ultimately expected to use them. Yet geography, socioeconomic factors, time commitments, awareness, language and cultural barriers all limit access to traditional site-based research.

Decentralized clinical trial (DCT) strategies reduce geographic and participation barriers by bringing selected study activities closer to patients through digital technologies, home health visits, community-based services, virtual sites and mobile sites. These flexible approaches expand access and trial reach while reducing patient burden.

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Building more accessible, patient-centric clinical trials

Decentralized clinical trial (DCT) strategies can help sponsors address barriers that have historically limited participation, from geography and time commitments to awareness, cultural and language challenges. By bringing elements of the trial closer to patients through virtual, mobile and community-based approaches, sponsors can create more flexible opportunities to participate.  

This white paper explores how a fit-for-purpose DCT strategy combines technology, services and operational support to:  

  • Expand access to more diverse and representative patient populations.  
  • Reduce patient and caregiver burden through flexible participation options.  
  • Support sites with the training and resources needed for effective DCT execution.  
  • Improve the patient experience with digital and decentralized solutions tailored to study needs.  
  • Advance trial sustainability while maintaining a focus on data quality and operational execution.  

Ultimately, decentralization is about more than adding technology to a protocol. Thoughtful DCT design makes clinical research more accessible and patient-centric while supporting sponsors’ diversity and study objectives.