ISPOR Europe 2026

Prescription trends and generic market share of heparinoid preparations in Japan from FY2014 to FY2024[c1.1]: A longitudinal claims database study

Dimitra Lambrelli et. al

Leveraging specialist ophthalmology EMR data to evaluate real-world effectiveness of anti-VEGF therapies for diabetic macular edema

Nick Boucher, Nitika Aggarwal, Mark Yates

Health state utilities associated with otoferlin-related hearing loss

Louis S. Matza, Timothy A. Howell, Nick C. Patel, Peter Quon, Paul Sommer, Ivette Cejas, Donald M. Goldberg, Jameel Muzaffar, Chad Ruffin

Health state utilities associated with treatment for transfusion-dependent ß-thalassemia in France

Louis Matza, Adeline Durand, Katie D. Stewart, Jennifer Drahos, Gabriela Vega-Hernandez

Changes in the number of pregnancy and lactation post-marketing requirements/commitments issued by the FDA after the release of the draft post approval pregnancy safety studies guidelines in 2019

Yassaman Vafai

Cost implications of declining MMR coverage in England: A two-cohort analysis of NHS burden and catch-up vaccination value

Kerry Winter

MLUMR: An R package for population-adjusted indirect comparisons using multilevel unanchored meta-regression

Ahmad Sofi-Mahmudi, Conor Chandler

Estimating the UK population eligible for late-line multiple myeloma therapies using an epidemiological model

Kang Kang, Shujun Li, Denise Zou

Understanding evidence and reimbursement pathways for oncology retreatment: A cross-country assessment of regulatory, guideline, and HTA perspectives

Anna D’Ausilio, Himani Jaiswal, Caroline Delaitre-Bonnin

Comparison of GPT-5 models for artificial intelligence (AI)-assisted data extraction from randomized clinical trials (RCTs) in systematic literature reviews (SLRs): Accuracy, reproducibility, and time-efficiency

Mariana Farraia, Aiswarya Shree, Archana Rajadhyax, Anuja Pandey, Sohan Nitin Deshpande, Carolina Casañas i Comabella

Mental health HEOR evidence generation and growth of real-world evidence amid increasing disease burden: An AI-assisted longitudinal analysis, 2014–2023

Corrina Mau, Weicheng Ye, Thitima Kongnakorn

Fit-for-purpose recruitment in decentralized observational studies: Innovations, use cases, and design considerations

Elizabeth Donahue, Alison Rushby, Christopher Morris, Neil R. Brett

An AI- enabled digital twin for simulating anti-VEGF treatment strategies in real-world nAMD care

Ashwin Rai, Ariel Berger

Content validity evaluation of selected patient-reported outcome measures for pain, fatigue, and physical functioning in adults, adolescents, and children living with Osteogenesis Imperfecta

Elizabeth Gibbons, Laura Kelly, Savita Bakhshi Anand, Stephanie Bascle, Joshua Maher, Tracy Hart, Cemre Robinson, Ethen Cheng, Ingunn Westerheim

A mapping gap in the new UK EQ-5D-5L era: Implications for health technology assessment

George Bungey et.al

Early economic and pathway impact of incorporating novel mass spectrometry-based testing into treatment response assessment for multiple myeloma

Gregory L. Price, Teofilo Borunda Duque

Assessing orphan medicines under the European union (EU) health technology assessment regulation (HTAR): Is current HTA guidance fit for purpose?

Andreas Freitag, Elena Aruffo, Hefin Thoma, Caroline von Wilamowitz-Moellendorff

PICO provenance evaluating AI traceability for EU joint clinical assessments

Hanna-Liisa Vilu, Victoria Molenkamp, Rhythm Arora

Beyond expected outcomes: A framework to account risk aversion when eliciting patient preferences for treatment pathways in oncology

Hui Lu, Sebastian Heidenreich, Anup Das, Nicolas Krucien

A practical framework for including dietary data in real-world evidence studies: Lessons from inflammatory bowel disease and paediatric rare diseases

Neil Brett, Garthiga Manickam, Liz Donahue, John Sampalis, Susan Oliveria

Development of an integrated framework and AI-assisted platform for trustworthy regional healthcare data utilization in China

Zhen Luo, Hang Xu, Dimitra Lambrelli, Lu Ban

Adapting RWE methods to Japan: A practical framework for regulatory, ethical, and site-level implementation

Mika Kawaguchi, Tadashi Koga, Marina Yamamoto, Dimitra Lambrelli

Applying a framework to characterise the evolution of integrated scientific advice

Jennifer Boss, Emily Hearne, Marine Beugre-Guyot, Almudena Olid Gonzalez

The sensitivity analysis paradox in target trial emulation: An empirical taxonomy of bias mitigation and protocol design in 208 studies

Alban Fabre et.al

What drives positive NICE healthtech decisions? A review of economic evaluation evidence from recent appraisals

Vladislav Berdunov, Claire Spencer

From approval to access: Time to reimbursement decision for biosimilars in the EU-4

Alexandra Kumichel, Maria Dvorkina, Katherine Gibbs

Should we collect patient preference insights in registries? Findings from the PPD CorEvitas Obesity Registry

Hui Lu, Kevin Patrick Marsh, Sebastian Heidenreich, Jennifer Whitty, Anup Das, Nicolas Krucien, Heather Chubb

Closing the language gap in HEOR reviews: Validating AI-assisted screening of Chinese-language evidence

Caroline von Wilamowitz-Moellendorff, Aiswarya Shree, Andreas Freitag, Caoimhe Rice, Mireia Raluy Callado, Jade Thurnham, Ziyi Li, Lu Ban

Feasibility of identifying HR+/HER2− metastatic breast cancer and CDK4/6 inhibitor-treated cohorts in a Japanese multicenter oncology EMR database

Motoki Kuzuya, Shigemi Matsumoto, Ayanori Fukushima, Dimitra Lambrelli, Tadashi Koga, Masafumi Okada, Manabu Muto

Beyond claims data: A legally governed integrated EHR-claims database for real-world evidence generation in Japan

Dimitra Lambrelli et.al

Environmental impact assessment for total knee replacement care pathway and subsequent prosthetic joint infection

Eva Fuchs, Tom Binstead, Caoimhe T Rice

A mathematical appraisal of the family and caregiving effects framework in modeling caregiver spillover effects

George Bungey et. Al

Real-world treatment patterns in chronic lymphocytic leukemia: A systematic review

Magdalena Monica, Monika Reczek, Pawel Kawalec, Katherine Gibbs

The best of both worlds? hybrid programmatic-ai workflows for HTA-grade evidence generation for time-to-event analysis interpretation and reporting

Simone Rivolo, Tereza Lanitis, George Bungey, Michalis Galanakis, Ivan Houisse, Jack Ishak

Using tokenization to overcome limitations of claims data to identify use of remote patient monitoring among patients with peritoneal dialysis

Firas M. Dabbous, Divya Shridharmurthy, Rhonda Shaw, Samuel Huse, Kathryn Evans, Vanessa Danielson, Ariel Berger

Real-world evidence (RWE) readiness for EU Joint Clinical Assessment: Gap analysis between current RWE studies and EU HTA expectations

Neil Brett, Garthiga Manickam, Deborah Tallarigo, Susan Oliveria, Jack Ishak, Roy Mootooswamy

Progression of metabolic dysfunction-associated steatohepatitis and economic burden: Use of real-world health record data in England to inform economic models

Jennifer A. Davidson, Hannah R. Brewer, Caoimhe Treise Rice, Sara J. Carvalho, Yestle Kim

Prevalence of potentially inappropriate prescribing (PIP) in older adults in 2025 in the United States: Can we do better in the digital age?

Kathryn Evans, Ade Agbemuko, Harmony Omeife, Ariel Berger

Estimating the fiscal impact of menopause symptoms in England and Wales: A public finance framework for the evaluation of menopause interventions

Kinga Marczell et. al