Choosing Decentralized Clinical Trials

The Rise of DCTs

The COVID-19 pandemic has challenged the viability of traditional clinical trials around the world. The use of decentralized clinical trial (DCT) options was on the rise before the pandemic, but the industry’s growing need to keep research moving forward and ensure the safety of clinicians and patients made the need for remote capabilities more important than ever. With new efficiencies produced by telemedicine, remote monitoring, direct-to-patient shipments, devices and more, these new options will remain an important attribute of clinical trials as we enter the digital age of research.

0 %

of respondents expect to run a hybrid/decentralized trial in 2022 (vs. 59% in 2021).

Why Choose DCTs

As the clinical landscape continues to evolve, DCTs present opportunities to emphasize convenience, safety and flexibility, while continuing to pursue quality data and valuable research. Advantages include:


reduction in recruitment timelines1, 2


increased trial retention
rates3, 4


increased patient interest4


patients recruited from communities of color1, 4


of study team members believe data quality can be higher5


In 2021, after pandemic-fueled growth in decentralized clinical trials, PPD mined industry opinions on the likely future composition of clinical trial operations. The analysis aimed to determine how hybrid and fully decentralized models will be used alongside traditional constructs in efforts to increase efficiency, improve outcomes, and speed the progress of life-saving therapeutics.

Access the data and insights on how the industry is pivoting to tackle clinical trials during the pandemic and beyond.

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Information Services Group (ISG) recognized PPD in its 2020 ISG Provider Lens™ Life Sciences Digital Services Global Report. The honorees were determined following a nine-month research study, in which providers were independently evaluated. The findings recognize PPD as an ISG Provider Lens Leader for digital transformation services, specifically its clinical development and patient engagement solutions.

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To guide organizations through a transformative time in clinical research, PPD held a number of webinars exploring the accelerated pace of adoption for novel approaches and innovations impacting clinical research, with our experts offering strategies and considerations to support the rapid changes happening within clinical trial design and operations.

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Examining Implementation Timelines For Decentralized Clinical Trials (Dcts)

While DCTs can still enable trials that would otherwise be challenging during the pandemic, many of the potential efficiencies — particularly rapid implementation — can remain out of reach. PPD has DCT strategies built into the protocol from the start, with custom features and functions instead of a one-size-fits-all approach.

Learn more about implementation timelines for decentralized trials.

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Building Decentralized Clinical Trials for Patients and Clinicians

The increased implementation of decentralized clinical trials means the industry now has a considerable body of evidence and experience to test the strengths of digital clinical trial models. With the growing amount of data comes the ability to assess how to make trials more effective and efficient, including a closer look at qualitative sponsor, site and patient feedback. To gain further insight into this transformation, PPD explored the experiences that key stakeholders have had when approaching decentralized clinical trials.

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Article Image – Protecting Clinical Research and Patients Through Decentralized Trial Strategies

Protecting Clinical Research & Patients Through Decentralization

Today’s biopharma and biotech organizations are increasingly opting for digitally enabled trial designs over traditional solutions. PPD® Digital works closely with life science leaders from around the world to navigate evolving trends in drug development, including the design and execution of bespoke decentralized clinical trials.

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Digital Innovation & Implementation

How can PPD’s suite of digital capabilities and solutions help you reach more patients?